Each 5-Way Calf Scour Bolus contains 500 mg oxytetracycline hydrochloride, a broad-spectrum antibiotic for use in beef and dairy calves. Recommended for the treatment and control of bacterial enteritis (scours) caused by Salmonella typhimurium and E. coli, and bacterial pneumonia (shipping fever, pasteurellosis) caused by Pasteurella multocida.