Pramitol 25E is a nonselective herbicide that can be applied in water or oil before or after plant growth begins. Although Pramitol 25E has considerable activity through foliar contact, much of its activity is through roots; therefore, its effectiveness is dependent on rainfall to move it into the root zone. Very dry soil conditions and lack of sufficient rainfall may result in poor weed control. Use only in areas where complete control of all vegetation is desired, such as industrial sites, right-of-way, lumberyards, petroleum tank farms, around farm buildings, and along fence lines. When applied to the soil, this product usually inhibits plant growth for a year or more.